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About the project In the BIOSTOP Study ulcerative colitis patients in remission after at least one year anti-TNF maintenance therapy will be included.

The electronic case report file is set up and maintained by Cecilie Moe at Unit for Applied Clinical Research AKF at Oslo University Hospital.

To identify factors predictive for successful restart of anti-TNF in patients experiencing a relapse Resource utilization, cost-effectiveness and patients reported outcome objectives• Control group patients, and intervention group patients who has restarted anti-TNF, will in addition be regularly monitored by anti-TNF drug concentration and antibody measurements.

Roger Aase ble tatt opp av Den norske Frimurerlosjen i 1993.

continuing anti-TNF in UC patients in remiss.

If clinical remission is confirmed by symptom score and faecal calprotectin, a full ileocolonoscopy is performed.

To identify factors predictive for successful discontinuation of anti-TNF• Foundation for the randomized part of the study 2017 — 2021 is granted by the Norwegian Research Council and MR Hospital Trust, and also the last 2 years will be partially financed by MR Hospital Trust• The study will be organized and conducted in cooperation with Norwegian Clinical Research Infrastructures Network NORCRIN at the Norwegian University of Science and Technology NTNU.

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Pris kr 350 spar kr 49.

During the randomization period, patients will be monitored by repeated symptom scoring and faecal calprotectin.

Roger Karsten Aase ble tatt opp i Den Norske Frimurerlosjen i 1993.